Race Against Time: ‘Today’ Anchor Savannah Guthrie’s Mother Missing Without Life-Sustaining Medication

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'TODAY' Anchor Savannah Guthrie's Missing Mom Without Daily Meds Needed to Survive
CREDITS: Wikimedia CC BY-SA 3.0

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'TODAY' Anchor Savannah Guthrie's Missing Mom Without Daily Meds Needed to Survive

A Concerning Vanishing Act (Image Credits: Pixabay)

Catalina Foothills, Arizona – The sudden vanishing of 84-year-old Nancy Guthrie from her longtime home sparked a frantic response from authorities and loved ones alike.[1][2]

A Concerning Vanishing Act

Nancy Guthrie disappeared from her residence near East Skyline Drive and North Campbell Avenue on Saturday evening, January 31, 2026. Family members last saw her around 9:30 to 9:45 p.m. A friend from her church noticed her absence at Sunday morning Mass and alerted one of her adult children.[1] That prompted a check of her home, followed by a 911 call around noon.[3]

The upscale Catalina Foothills neighborhood, where Nancy had lived since 1975 in a million-dollar home with a pool, suddenly became the center of a high-stakes probe. Pima County deputies arrived swiftly, but initial searches yielded no trace. Homicide detectives soon joined, signaling the gravity of the situation.[4]

Sheriff Declares Crime Scene

Pima County Sheriff Chris Nanos addressed reporters on Monday, describing elements at the home as “suspicious in nature.” He confirmed investigators processed the property as a crime scene, stating, “We believe now, after we processed that crime scene, that we do, in fact, have a crime scene, that we do, in fact, have a crime.”[2] Nanos emphasized Nancy “did not leave on her own.”[1]

The sheriff noted her sharp mental acuity – “of great sound mind and sharp as a tack” – ruling out dementia or wandering. Yet her physical limitations stood out: she could not walk 50 yards unaided. Search and rescue efforts, including helicopters with infrared cameras and drones, wrapped up without success. The FBI stayed aware as the focus shifted to criminal inquiry. Family members cooperated fully, with Nanos adding that Savannah Guthrie stayed in touch.[2][1]

Dire Medical Urgency

The clock ticked faster due to Nancy’s health needs. Authorities revealed she required daily medication essential for survival. Sheriff Nanos warned that without it in 24 hours, the outcome “could be fatal.”[2] Her limited mobility compounded the risks, leaving her vulnerable in unknown circumstances.

Colleagues highlighted this peril during Monday’s broadcasts. The situation turned a missing persons case into a potential tragedy, prompting widespread calls for tips to the Pima County Sheriff’s Department at (520) 351-4900.[5]

Emotional Outpouring from ‘Today’ Family

Savannah Guthrie missed the “Today” show Monday, her absence underscoring the personal toll. Longtime co-host Jenna Bush Hager grew emotional on “Today with Jenna & Sheinelle,” opening with, “We need to start the show with something that is deeply personal for us this morning.”[4] She shared, “Nancy Guthrie, Savannah’s beloved mom and somebody we adore around here, has been reported missing in Arizona,” adding that Nancy takes daily medication “for survival” and was likely without it.[5]

The Guthrie family issued a statement confirming the missing persons report and their close work with law enforcement. They expressed thanks for public support and urged anyone with information to come forward. Jenna closed by saying, “Our prayers obviously go out to Savannah.”[4]

Key Takeaways

  • Nancy Guthrie, 84, last seen at home Saturday evening; reported missing Sunday noon.
  • Pima County treats case as crime; suspicious scene, no voluntary departure.
  • Daily medication critical – fatal risk after 24 hours without it.

As investigators press on, the blend of foul play suspicions and medical peril keeps tension high. Nancy’s safe return remains the overriding hope for her family and fans. What do you think about this developing story? Tell us in the comments.

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